The AESOP-10 study is a 10-year follow up of an epidemiologically characterized sample of 535 individuals initially studied during their first episode of psychosis that aims to identify the factors that predict the course and outcome of psychosis following a first episode, focusing specifically on the role of biological and social risk indicators, cannabis use, and duration of untreated psychosis (DUP). The study also works to examine and explain the differences in the course and outcome of psychosis in Black and White patients in the decade following a first episode of psychosis.