The Armed Services Trauma Rehabilitation Outcome (ADVANCE) Study is a prospective longitudinal cohort study investigating the long-term physical and psychosocial outcomes of UK military personnel who sustained severe combat-related trauma during the Afghanistan conflict. ADVANCE aims to study the incidence of a wide variety of outcomes, including cardiovascular and musculoskeletal disease, mental health, functional and social outcomes, quality of life, employment, and mortality. Data is collected using various methods, including self-report questionnaires and clinical assessments.