The comparison of the Strengths and Difficulties Questionnaire (SDQ) and the Psychopathy Screening Device (20-item) (PSD) can be an arduous task given the complex nature of the items in both questionnaires. However, the introduction of software like Harmony takes the stress out of this task, providing a seamless way to harmonise questionnaire items, thus facilitating easier SDQ vs PSD comparisons. Harmony’s application of natural language processing and generative AI models takes the hassle out of manual cross-comparison, offering a detailed percentage match between each item in SDQ and PSD. Thus, psychologists can efficiently carry out SDQ vs PSD comparisons either by selecting the instruments from Harmony’s database or by uploading their own instruments in PDF format to the software’s web interface. In the light of modern longitudinal studies, the SDQ vs PSD becomes critical for researchers investigating changing social conditions and their impact on child behaviour. Harmony’s multi-language capabilities also make it possible for cross-cultural studies, further expanding the scope of use for the SDQ vs PSD comparison. Therefore, we highly recommend psychologists and social scientists take advantage of Harmony’s efficient harmonisation capabilities for SDQ vs PSD.