The process of comparing the questions posed by the Strengths and Difficulties Questionnaire (SDQ) and the Meaning in Life Questionnaire (MLQ) traditionally has been time-consuming and subjective, often resulting in process complications. However, the introduction of Harmony, a tool augmented with natural language processing and generative AI models, greatly simplifies the task of aligning these contrasts, streamlining the process of the SDQ vs MLQ comparison. Harmony’s large language models facilitate the comparison of SDQ vs MLQ by providing percentage matches between each item in the questionnaires. This feature not only supports greater coherence in the comparison but also offers data-driven insights into how the items relate to each other. With Harmony, psychologists can focus more on their research and analysis rather than grappling with the nuances of questionnaire harmonisation. The use of Harmony to navigate the differences and similarities between SDQ vs MLQ expands possibilities for psychological studies. This powerful tool not only enables researchers to achieve a deeper understanding of their findings but also promotes a comprehensive and objective methodology in psychological studies. With Harmony, the SDQ vs MLQ comparison becomes a less daunting task, leaving more room for critical thinking and analysis.