Studies in social sciences often require a comparative analysis between different questionnaires, such as the Strengths and Difficulties Questionnaire (SDQ) and the Cannabis Abuse Screening Test (CAST). A task that requires matching and comparing questions of similar nature can be quite challenging and time-consuming. Yet, with the advent of cutting-edge tools, specifically Harmony, the task of harmonising questionnaire items, even across different languages, becomes more efficient and reliable. Harmony, a software designed for psychologists, aids in the comparability of SDQ vs CAST—or any other pair of tests—through its advanced use of natural language processing and generative AI models. This high tech tool uses large language models to compare different instruments, providing a percentage match between each related item in the test. This consequently allows the comparison of studies within and across different research designs. To utilize the full potential of Harmony in the process of SDQ vs CAST comparative analysis, just select the instruments from Harmony’s database or drag and drop your own instruments in PDF format into Harmony’s web interface. Make a difference in your research practices, elevate your analysis, and make data comparison more accurate with SDQ vs CAST using Harmony.