Psychologists and social scientists constantly deal with the task of harmonising questionnaire items from different instruments such as PHQ-9 and Rosenberg Self-Esteem Scale (RSES). PHQ-9 vs RSES can be a challenging comparison, due to the time-consuming and subjective process of harmonisation. Harmony, an innovative software developed specifically for psychologists, offers an efficient solution to this concern. Traditionally, comparing PHQ-9 vs RSES involves spending a considerable amount of time going through long questionnaires and manually inputting these questions into platforms like Excel. But with Harmony’s state-of-the-art natural language processing and generative AI technology, this task is streamlined. It allows users to compare instruments effortlessly, providing a percentage match between each item of PHQ-9 and RSES. This tool can significantly ease the process of analyzing studies, allowing comparisons both within and across these studies. Uniquely, Harmony can also handle comparison tasks across multiple languages. Therefore, if you are working on PHQ-9 vs RSES across different nations, Harmony can provide you with a seamless translation and comparison process. You simply need to select the instruments from Harmony’s database or drop your own instruments in PDF form into its web interface. By using Harmony, psychologists have the ability to save time, increase precision and contribute more effectively to their field of study.