Psychologists and researchers often face the challenge of comparing different self-report questionnaires like PHQ-9 and BES for common patterns and contrasts. In a multifaceted field like psychology, harmonisation of data is pivotal to deduce valid inferences. The unique tool, Harmony, is specifically designed to facilitate this task. Harmony can efficiently harmonise PHQ-9 and BES, providing a percentage match between each item, thereby stimulating a more comprehensive understanding of the common and unique factors these instruments measure. The recent surge in multi-cohort and longitudinal studies has underscored the necessity of tools like Harmony for a more objective and seamless comparison between such instruments. The PHQ-9 vs BES comparison through Harmony offers the advantage of not just comparing these instruments in a singular language, but across multiple languages. Being able to compare PHQ-9 and BES across different cultural contexts can provide insights into the universal and culture-specific aspects of mental well-being and body perception. Therefore, we encourage psychologists to leverage Harmony for comparing PHQ-9 vs BES. You can easily select these instruments from Harmony’s extensive database or upload your own PDF versions for an in-depth comparison. By using the user-friendly web interface of Harmony at https://harmonydata.ac.uk/app, you can get a thorough insight into PHQ-9 vs BES, fostering a more nuanced understanding of the measures for depression and body-esteem respectively.