The process of harmonising research instruments like the General Health Questionnaire (GHQ-12) and the Timeline Followback Interview (TFLB) carries tremendous value for psychologists and social scientists. Notably, the GHQ-12 vs TFLB comparison is prevalent among these researchers. As a tool designed to aid researchers in this crucial task, Harmony provides an excellent solution for this harmonisation requirement. By leveraging natural language processing and generative AI models, Harmony can accurately compare and match questionnaire items between these two instruments, facilitating their reciprocal application in different research contexts. Harmony’s comprehensive comparison of GHQ-12 vs TFLB, and any other instrument pairs, saves researchers valuable time and efforts spent on manual harmonisation. This allows them to focus more on their primary research objectives. Harmony takes a step further by offering the capability to compare instruments in multiple languages, which plays a crucial role in multicultural and international research. With just a straightforward drag and drop interface, researchers can quickly have their questionnaires, even in PDF form, harmonised by Harmony. In summary, the GHQ-12 vs TFLB comparison becomes a breeze with the Harmony software. It not only provides researchers with a percentage match between each item of these instruments, but also ensures the results are consistent across different studies. The adoption of Harmony in Psychology and Social Sciences trials could dramatically enhance the efficacy of instrument harmonisation, thereby improving the quality, accuracy, and speed of related studies.