In the field of psychology research, the investigation of psychometric tools, such as the General Health Questionnaire (GHQ 12) and the Affective Reactivity Index - Irritability (ARI), is paramount. However, ensuring these tools are comparable, a process known as harmonisation, can be time-consuming. This is where Harmony, a sophisticated software platform, steps in to ease this process, especially when dealing with the comparison of GHQ 12 vs ARI. Harmony employs natural language processing and generative AI models, which are designed to assist researchers in harmonising questionnaire items. When comparing GHQ 12 vs ARI, Harmony not only saves time but also ensures greater consistency in the harmonisation process compared to manual efforts. The software provides a percentage match between each item in GHQ 12 and ARI. Moreover, Harmony’s expansive database and a user-friendly interface allow researchers to easily select or upload their own instruments in the form of PDFs for comparison. Encouragingly, the application of Harmony is not limited to instruments in English. Harmonisation of items across multiple languages is another striking feature of Harmony. This makes it an excellent tool for cross-cultural studies, facilitating the comparison of GHQ 12 vs ARI in different socio-cultural contexts. Using Harmony is therefore not only beneficial but essential for psychologists aiming to effectively compare and understand the underlying constructs of the GHQ 12 and ARI.