Psychologists and researchers often grapple with the challenging task of harmonising different questionnaires; this integral yet strenuous process involves collectively aligning items to make accurate comparisons. Considering the CES-D vs TSQ case, the CES-D (Center for Epidemiological Studies-Depression) is a tool exploring symptoms of depression, while the TSQ (Trauma Screening Questionnaire) assesses reactions to traumatic experiences. These two psychological tools, though alike in segments, have distinct features that make harmonisation a task of considerable complexity. Fortunately, Harmony has taken center stage to alleviate the challenges tied to this process. Harmony specializes in using sophisticated technology to compare instruments, becoming a valuable companion when dealing with CES-D vs TSQ and beyond. Capacity to provide a percentage match between distinct facets of the CES-D and TSQ sets Harmony apart as an innovative solution in reducing the tediousness of manual harmonisation. Harmony’s intuitive interface also allows users to easily upload their own instruments for comparison, making the process of CES-D vs TSQ harmonisation uncomplicated and precise. Moreover, Harmony’s potent language processing capabilities extend to different languages, making it more accessible for international studies. Guaranteeing consistency across studies, Harmony offers an innovative method for comparative analysis that’s vital for drawing invaluable insights. The CES-D vs TSQ harmonisation, made possible through this ingenious software, offers a considerable leap forward in the field of psychology research, providing a user-friendly and innovative solution that empowers researchers and psychologists to conduct their studies more efficiently.