Psychologists and researchers often face the challenge of harmonising and comparing different psychological questionnaires. One common comparison is between the Center for Epidemiological Studies-Depression (CES-D) and the Scale for the Assessment of Negative Symptoms (SANS). The CES-D vs SANS comparison can be quite challenging, considering each questionnaire possesses unique features and attributes.Fortunately, the Harmony software provides a solution. Harmony, developed specifically for researchers, uses natural language processing and generative AI models to facilitate and simplify the process of harmonising questionnaires. When comparing CES-D vs SANS, for instance, Harmony can identify similarities between each item in both questionnaires, offering a percentage match. This enables accurate comparisons and powerful insights, saving researchers valuable time and effort in manual analysis. Harmony’s large language models allow for detailed comparisons, not just in English, but in multiple languages. Harmony can be a versatile tool in psychology research. Psychologists looking to compare CES-D vs SANS can simply select these instruments from Harmony’s comprehensive database or upload their own versions. Harmony’s user-friendly web interface makes matching and comparing questionnaires efficient and convenient. By exploiting the versatility of Harmony, researchers can more accurately evaluate and compare the CES-D and SANS, providing robust and conclusive outcomes in psychology research.