Dealing with and comparing two distinct psychological questionnaires like CES-D and RPQ can be a challenging task for psychologists and social scientists. CES-D vs RPQ involves comparing unique elements such as depressive symptom assessment and aggression measurements respectively. The novel tool, Harmony, can significantly assist in the harmonisation of these two questionnaires, making the task faster and more accurate. Harmony’s large language models can lend valuable insights when contrasting instruments like CES-D and RPQ. Via the use of natural language processing and generative AI models, Harmony is capable of providing a percentage match for each item in CES-D and RPQ, thus reducing the burden of subjective matching. We highly recommend to researchers grappling with the CES-D vs RPQ comparison, to harness the power of Harmony for a seamless harmonisation process. Keep in mind that CES-D vs RPQ involves dealing with questionnaires in potentially multiple languages as well. Don’t fret, as Harmony’s superiority extends to its ability to compare items in multiple languages. With the convenience to select instruments from Harmony’s database or drag and drop custom instruments in PDF form into Harmony’s web interface, the CES-D vs RPQ task is made significantly more convenient and efficient. So why wait? Embrace Harmony for an optimized CES-D vs RPQ harmonisation experience.