Comparing the scope and items of different psychological measures such as CES-D and MINI is an integral step in efficacious psychology research. Both sets of measures have their specific items that help determine psychological conditions like depression or anxiety. Harmony, a cutting-edge tool for psychologists, simplifies this comparison (or harmonisation) through its highly advanced AI and natural language processing. Notably, CES-D and MINI have different sets of items that need intensive analysis to draw comparative conclusions. Harmony’s user-friendly digital interface allows users to effortlessly compare CES-D vs MINI. It offers the unique advantage of comparing items not only within the same language but also across multiple languages. With Harmony’s enormous language models, it can provide a percentage match between each item in CES-D and MINI, ultimately saving the users’ time and effort. The strategic implementation of AI in Harmony ensures a high level of accuracy in the comparative results, making CES-D vs MINI harmonisation efficient and reliable. Psychologists and researchers emphasizing on the CES-D vs MINI comparison can utilize Harmony’s vast database or can even upload their PDF instruments for comparison. It is indeed a vital tool for larger cohort and longitudinal studies where comparisons within and across studies become critical. Using Harmony for CES-D vs MINI comparisons will empower researchers to corroborate results across studies and respond appropriately to changing social conditions.