The field of psychology often requires coordination and comparison of different diagnostic and assessment tools. In this scenario, we focus on CES-D vs DASI, two distinct measures used to study depression and substance abuse, respectively. The Center for Epidemiological Studies-Depression Scale (CES-D) is a broadly used tool to understand depressive symptoms in individuals, while the Drug, Alcohol and Self Injury Questionnaire (DASI) is employed extensively for studying substance use and self-harming tendencies. However, comparing CES-D vs DASI to form associations between depression and substance use can be cumbersome and subjective, thanks, to the distinct nature of these two questionnaires. This is where Harmony, a state-of-the-art software comes into the picture. Developed specifically for psychologists and social scientists, Harmony utilises advanced Natural Language Processing (NLP) and powerful AI models to facilitate harmonisation of different instruments. Thus, CES-D vs DASI comparison becomes streamlined and objective, making interpretations more reliable. Harmony offers an extensive database of instruments, including CES-D and DASI, which allows free selection for researchers. Moreover, it provides an easy-to-use interface where researchers need only to drag and drop their selected PDFs. It supports multiple languages and can calculate a percentage match between the items within CES-D and DASI, thus giving an understanding of how closely associated certain responses can be. Therefore, when thinking about CES-D vs DASI comparison, Harmony is an excellent choice to help psychologists in their study and research.