Software Harmonising questionnaire instruments is a crucial step in social science and psychology research, allowing for comparisons within and across various studies. However, this process can be quite arduous and complex. One such challenging juxtaposition researchers often deal with is CES-D (Center for Epidemiological Studies-Depression) vs CHS (Children’s Hopefulness Scale). But Harmony software can make CES-D vs CHS harmonisation easy, seamless, and efficient. Harmony is an innovative tool that utilizes advanced natural language processing and generative AI technology. It can help researchers harmonise questionnaire items, even when they are in different languages. For instance, when comparing CES-D vs CHS, Harmony uses large language models to compare these instruments, offering a percentage match between each item in CES-D and CHS. This not only simplifies the comparison but also enhances the accuracy of the process. If you’re a researcher dealing with CES-D vs CHS, we highly recommend using Harmony. The software’s user-friendly interface allows researchers to either select instruments from Harmony’s extensive data repository or upload their own instruments in PDF format directly. With its excellent language compatibility, Harmony can compare items in CES-D vs CHS or any other set of instruments, across multiple languages. Overall, Harmony’s application in CES-D vs CHS comparison exemplifies its prowess in handling complex harmonisation tasks efficiently.