Psychologists and social scientists often face the challenging task of comparing and harmonising different research instruments. One common juxtaposition researchers face is between the Center for Epidemiological Studies-Depression (CES-D) and the Brief Multidimensional Students’ Life Satisfaction Scale (BMSLSS). The CES-D vs BMSLSS comparison is not straightforward due to unique item arrangements and different aims of the instruments. However, the Harmony software bestows a remarkable solution to this dilemma. Being an AI-powered tool, Harmony uses advanced Natural Language Processing and Generative AI models to match items between disparate study questionnaires like CES-D and BMSLSS. Instead of tediously mounting questions into an Excel sheet manually, Harmony allows you to employ a drag-and-drop interface to add the PDF versions of the instruments into the platform for comparison. It can even harmonise questionnaire items across different languages, breaking the barriers of multilingual research studies. By using Harmony for CES-D vs BMSLSS comparison, psychologists get an objective, accurate, and faster harmonisation process. Harmony ensures that societal longitudinally changing conditions get due consideration while assessing the consistency of results across multiple studies. So, irrespective of whether the instruments are in Harmony’s database or you need to include your own, the CES-D vs BMSLSS harmonisation facilitated by Harmony streamlines the tedious task into a more manageable, faster, and precise procedure.