Psychologists and social science researchers often have the task of comparing different instruments of psychological measurement. A great example of this is the comparison of CES-D (The Center for Epidemiological Studies-Depression) and ARI (Affective Reactivity Index - Irritability). In order to perform this comparison effectively and methodologically, Harmony, a sophisticated tool for harmonisation of questionnaire items, can be a game-changer. Harmony employs natural language processing and generative AI models to compare and harmonise items from CES-D and ARI with efficiency and precision. Harmony makes the comparison of CES-D vs ARI much easier, simpler and more reliable. Researchers can rely on Harmony’s vast database or can drop their very own instruments in PDF form into the Harmony software via its web interface. Furthermore, Harmony offers the advantage of comparing items in numerous languages, which enables broader research scope and flexibility. CES-D vs ARI comparison can easily be done in a matter of few clicks, saving a lot of time, while enhancing comparison accuracy. In conclusion, Harmony simplifies the process of CES-D vs ARI comparison by using large language models to compare instruments and providing a percentage match between each item. This promises more accurate, faster and reliable outcomes which better cater to the needs of psychologists and social scientists in their research. Therefore, for an efficient CES-D vs ARI comparison, Harmony could be an indispensable tool that serves as a stepping stone to successful and insightful research.